Are you taking Fosamax, Actonel or Boniva? These medications, called bisphosphonates,
are used to help treat osteoporosis by increasing bone density. However, taking these
medications for an extended time can cause poor bone healing after dental surgeries. 
What is Actonel used for?
Actonel [risedronate sodium tablets] is used to treat PagetÂ’s disease of the bone.
Actonel is also used to prevent and treat: postmenopausal osteoporosis, glucocorticoid-induced
osteoporosis in men and women
Who should not take Actonel?
You should not take Actonel if you: have low calcium levels in the blood, have bone or mineral
problems that have not been treated by your health care provider, have severe kidney problems, are
unable to stand or sit up for at least 30 minutes.
General Precautions with Actonel:
Tell your doctor if you have a history of stomach problems because Actonel can cause difficulty
swallowing, inflammation of the esophagus, esophageal ulcer, and stomach ulcer.
If you have a bone-imaging test, tell your doctor or technician you are taking Actonel because it can
interfere with the test.
What should I tell my doctor or health care provider:
Tell your doctor or health car provider if you are:
taking aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDS), because taken togetherwith
Actonel, aspirin and NSAIDS can increase the probability of stomach irritation.
trying to become pregnant, are already pregnant, or are breast-feeding.
What are some possible side effects of Actonel? (This is not a complete list of side effects
reported with Actonel. Your health care provider can discuss with you a more complete list of side
Side effects of Actonel are generally mild to moderate and do not require stopping the treatment.
The following is a listing of the most common side effects:
Sales and Market
The market for osteoporosis treatments is large, with 2007 global sales exceeding $8.9 billion for
drugs including Fosamax, Boniva, Actonel and Reclast. 
For more detailed information about Actonel, ask your health care provider.  Amgen asks FDA to approve osteoporosis drug www.forbes.
com Associated Press, 12.19.08, 04:10 PM EST  Fosamax and bone healing www.wnewsj.com 12/4/2008 10:42:00 PM
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