Some scientists working on anti-cancer diets have suggested anti-cancer diet or food
ingredients in scientific journals. Two recent review articles on anti-cancer diet are as
follows:

FIRST ARTICLE ON ANTI-CANCER DIETS
Donaldson MS., Hallelujah Acres Foundation, pointed out that 30-40 percent of all cancers
can actually be prevented by lifestyle and dietary measures alone[1]. Obesity, nutrient
sparse foods such as concentrated sugars and refined flour products impair our glucose
metabolism. While, low fiber intake, consumption of red meat, and imbalance of omega 3
and omega 6 fats increase cancer risk.

Intake of flax seed, especially its lignan fraction, and abundant portions of fruits and
vegetables will lower cancer risk. Allium and cruciferous vegetables are especially
beneficial, with broccoli sprouts being the densest source of sulforophane. Protective
elements in a cancer prevention diet include selenium, folic acid, vitamin B-12, vitamin D,
chlorophyll, and antioxidants such as the carotenoids (alpha-carotene, beta-carotene,
lycopene, lutein, cryptoxanthin). Ascorbic acid could be very beneficial intravenously.
Supplementary use of oral digestive enzymes and probiotics also has merit as anticancer
dietary measures.

If a person can comply this anti-cancer diet, it is likely that he has at least a 60-70 percent
decrease in breast, colorectal, and prostate cancers, and even a 40-50 percent decrease
in lung and most other cancers.

SECOND ARTICLE ON ANTI-CANCER DIETS
Dorai T and Aggarwal BB, New York Medical College, state that consumption of certain
fruits and vegetables can reduce the risk of acquiring specific cancers. Most
phytochemicals derived from certain fruits and vegetables, are chemopreventive agents.
These phytochemicals are actually the key elements in an anti-cancer diet.

They include genistein, resveratrol, diallyl sulfide, S-allyl cysteine, allicin, lycopene,
capsaicin, curcumin, 6-gingerol, ellagic acid, ursolic acid, silymarin, anethol, catechins and
eugenol. These anti-cancer diet elements demonstrate ability of suppression of cancer cell
proliferation and inhibition of growth factor signaling pathways. They also can induce
apoptosis, inhibit NF-kappaB, AP-1 and JAK-STAT activation pathways, inhibit
angiogenesis, suppress the expression of anti-apoptotic proteins and inhibit
cyclooxygenase-2. These anti-cancer diet elements also have very recently been found to
reverse chemoresistance and radioresistance in patients undergoing cancer treatment!!

[1] Nutrition and cancer: A review of the evidence for an anti-cancer diet. Nutr J. 2004 Oct 20;3(1):19.
[2] Cancer Lett. 2004 Nov 25;215(2):129-40.

WHAT FOOD INGREDIENTS CAN BE USED IN ANTI-CANCER OR CANCER PREVENTION
DIETS, BASED ON RESEARCH FINDINGS?

REGULAR FOOD CAN BE AN ANTI-CANCER DIET
FISH High intake of fish is associated with lower risk of adenoma recurrence. Mothers eat
fish or other foods rich in omega-3 fatty acids during pregnancy and nursing, the risk of
breast cancer in their daughters can be reduced by about 40% in a study of
mice.[European Journal of Cancer Prevention 13(2): 159-164, June 2004]  Mom's Diet May Reduce
Breast Cancer Risk in Daughters, Health Day, April 20, 2005.

SOY Soy glucosylceramide (soy GlcCer) reduced the formation and growth of tumor cells
in the gastrointestinal tracts of mice. Soy may protect against endometrial cancer. [A
Report from HealthDay, May 20, 2004, Reuters Health, May 28, 2004]

MILK Calcium and milk consumption reduces colorectal cancer risk. However, high intake
of calcium may increase the risk of prostate cancer. [Megan Rauscher, Reuters, July 6, 2004]

TEA Some tea leaves contain Tea Polyphenols. Tea polyphenols demonstrate cancer
preventive properties by reducing abnormal cell growth and inflammation. The purified
component, epigallocatechin gallate (EGCG), prevent colon cancer. Recently, European
scientists found EGCG prevents cancer cells from growing by binding to a specific enzyme.
[Scientists identify green tea's cancer-fighter. Reuters, March 15, 2005].

VITAMINS CAN BE A PART OF THE ANTI-CANCER DIET
VITAMIN A High intakes of foods rich in vitamin A or its carotenoid precursors can reduce
risks of several types of cancers including breast cancer. [Nutrition Research Newsletter, March
1998, Technical Insights, John Wiley & Sons]

VITAMIN D Plenty of sunshine and vitamin D help fight against cancer at early stage lunc
cancer. Sun, Vitamin D Help Lung Cancer Survival - Study, Reuters, Mary 18, 2005.

VITAMIN E Vitamin E from plant sources may prevent bladder and prostate cancer.
Alpha-tocopherol may play a bigger role in an anti-cancer diet. Consume your vitamin E to
prevent some cancers, by Aimee M. Male, Oakland Tribune,  July 7, 2004.

However, high-dose vitamin E supplements may speed up latent cancers development.
Vitamin E supplements may speed up development of cancer, study says, PR Newswire, April 6, 2005

SUPPLEMENTS CAN BE ADDED TO ANTI-CANCER DIETS
BILBERRY Bilberry extract contains a chemical called anthocyanin. Epidemiological studies
indicated that a moderate consumption of anthocyanin products, such as biberry extract
or red wine is assoicated with a lower risk of cardiovascular disease and an improvement
of visual functions [Reference 1]. Hou divided its anti-tumor effects into three ways: (1)
antioxidation (2) anticarcinogensis and (3) apoptosis induction of tumor cells  Potential
Mechanisms of Cancer Chemoprevention by Anthocyanins, Curr Mol Med. 2003
Mar,3(2):149-59.

CAT's CLAW Sheng Y et al, Lund University, Sweden, identified C-Med-100 as the main
active ingredient of Cat's claw to inhibit cell growth without cell death, leading to DNA
repair, immune stimulation, anti-inflammation and cancer prevention.
[J Ethnopharmacol. 2005 Jan 15;96(3):577-84. Epub 2004 Dec 08].

Akesson C et al at Lund University, Sweden, provided direct evidence that C-Med 100
inhibited nuclear factor kappa B (NF-kappa B) activity and proposed that this at least
partially caused the inhibition of proliferation. They showed that a hot water Cat's claw
extract could inhibit T and B lymphocyte proliferation. This extract also did not interfere
with IL-2 production nor IL-2 receptor signaling. They further suggested that retarded cell
cycle progression caused the proliferation inhibition.
[Int Immunopharmacol. 2003 Dec;3(13-14):1889-900]

Danggui Longhui Wan Compounds derved from indirubin, a component of Danggui
Longhui Wan, block CDK and interrupt the normal cell cycle.
Traditional Medicine Derivatives Kill Cancer Cells, Reuters Health, April 18, 2005

GRAPE SEED EXTRACT grape seed extract was chemo-preventive from studies using
animal model of breast cancer.  Procyanidin B dimers in red wine and grape seeds could
be used as chemopreventive agents against breast cancer by suppressing in situ
estrogen biosynthesis.

HUMAN CHORIONIC GONADOTROPIN Human chorionic gonadotropin was found to
activate tumor suppressor genes and stop cancer cell growth in study of animals. Early
preganancy may cut breast cancer risk.
Pregnancy Hormone May Prevent Breast Cancer, WebMD, April 20, 2005.


GINSENG Kim et al concluded that ginsenosides Rg3 and Rh2 could inhibit the
proliferation of prostate cancer cells. [Effect of ginsenosides Rg3 and Rh2 on the
proliferation of prostate cancer cells. Kim et al., Pusan National University, Korea. Arch
Pharm Res. 2004 Apr; 27(4):429-35.]

GOTU KOLA Huang YH et al  found that gotu kola (asiaticoside)  induced apoptosis of
cancer cells and enchanced the anti-tumor activities of vincristine. The cancer cells studied
were KB, KBv200, MCF-7, and MCF-7/ADM. [Ai Zheng. 2004 Dec;23(12):1599-604]

Park BC et al found asiatic acid (gotu kola) induced apoptosis in SK-MEL-2 human cancer
cells via generation of ROS, alteration of Bax/Bcl-2 ratio and activation of caspase-3, but
p53-independent. [Cancer Lett. 2005 Jan 31;218(1):81-90].

Yoshida M et al, ound compounds from gotu kola had antiproliferative activities against
human gastric adenocarcinoma (MK-1 cancer), human uterine carcinoma (HeLa cancer),
and murine melanoma (B16F10 cancer) cells was estimated. [Biol Pharm Bull. 2005
Jan;28(1):173-5]

PYCNOGENOL Sime S and Reeve VE concluded that topical Pycnogenol offered significant
and dose-dependent protection from UV-induced acute inflammation, immunosuppression
and carcinogenesis (cancer), when applied to the skin after daily irradiation. [Photochem
Photobiol. 2004 Feb;79(2):193-8]

Huynh HT and Teel RW found that  pycnogenol selectively induced death in human
mammary cancer cells (MCF-7) and not in normal human mammary MCF-10 cells.
[Anticancer Res. 2000 Jul-Aug;20(4):2417-20]

RED CLOVER Jarred RA et al, found that the apoptosis in radical prostatectomy specimens
(cancer) from treated patients was significantly higher than in control subjects. They did
not find any adverse events. [Cancer Epidemiol Biomarkers Prev. 2002
Dec;11(12):1689-96]

Almost at the same time, Rice L et al concluded that biochanin A (from red clover) inhibited
prostate cancer cell growth through induction of cell cycle arrest and apoptosis. [Prostate.
2002 Aug 1;52(3):201-12]

ROYAL JELLY Inoue et al studied the effect of dietary Royal Jelly on tissue DNA oxidative
damge and on the life span of C3H/HeJ mice. They found that the levels of
8-hydroxy-2-deoxyguanosine (a marker of oxidative stress) was significantly reduced if
the mice were fed with Royal Jelly for 16 weeks. The dietary Royal Jelly also increased the
average life span of C3H/HeJ mice through the mechanism of reduced oxidative
damage.Royal Jelly prolongs the life span of C3H/HeJ mice: correlation with reduced DNA
damage. Inoue et al, Fujisaki Institute, Japan. Exp Gerontol. 2003 Sep;38(9):965-9.

Binclletto C. et al found royal jelly was able to produce effect on haematopoiesis of Ehrlich
ascites tumor-bearing mice. Their result showed that royal jelly prevented the
myelosupression. Effects produced by Royal Jelly on haematopoiesis: relation with host
resistance against Ehrlich ascites tumour challenge. Int Immunopharmacol. 2005 Apr;
5(4):679-88.


CANCER DiETS     (CARCINOGENS)

GROUP 1 - REGULAR FOOD

RED MEAT It is observed that colon cancer risk is related to red meat consumption in
Japan.[European Journal of Cancer Prevention 13(2): 127-132, April 2004]

Recent studies have shown that people with high percentage of transferrin saturation
(i.e. increased body iron stores) and who consume high levels of dietary iron (i.e. more
than 18 mg), or red meat have an increased risk of cancer and cancer mortality. Mainous,
III et al, Transferrin Saturation, Dietary Iron Intake, and Risk of Cancer, Annals of Family Medicine
3:131-137 (2005)

SWEET STUFF Cancer cells need sugars for growth.

FRIED FOODS
Fried foods contain various amount of acrylamide, a chemical has caused cancer in
laboratory rats. Acrylamide levels in food should be reduced because of public health concern says
UN expert committee.WHO March 2, 2005.

PROCESSED MEATS Processed meats such as hot dogs and sausages raises the risk of
pancreatic cancer. Hot Dogs Raise Risk of Pancreatic Cancer - study, Reuters, April 20, 2005.

CHOLESTEROL High blood cholesterol can make prostate cancers grow faster. Injection
of human prostate cancer cells into mice and feeding them with a high-cholesterol diet can
lead cholesterol accumulated in the outer membranes of the cancer cells. [High cholesterol
drives prostate cancer-study, Reuters, March 17, 2005]

SALTY FOOD such as Kimchi

GROUP 2 - FOOD SUPPLEMENTS

OVERDOSE CALCIUM Calcium and milk consumption reduces colorectal cancer risk while
high intake of calcium may increase the risk of fatal prostate cancer. [Megan Rauscher,
Reuters, July 6, 2004]

GROUP 3 -  DRINKS/PRODUCT

CARBONATED DRINKS
Carbonated drinks may raise the risk of esophageal cancer. Reuter Health, May 18, 2004

SMOKING
US Surgeon General suggested that smoking was linked for the first time to acute myeloid
cancers-ACS News Center, June 1, 2003

Dr. Rafi Nagler, Technion-Israel Institute of Technology in Haifa, explained that saliva
contained antioxidants, but cigarette smoke could destroys the molecules and turned
saliva into a dangerous compound.-Reuter Health, June 1, 2004

The Chemical and Veterinary Investigation Institute in Stuttgart, Germany, said they found
the carcinogen N-Nitrosamine present in 29 of 32 types of condoms. Reuter Health, May 28,
2004

Dr. Garth H. Rauscher, University of Illinois at Chicago found that hair dye use was a
potential risk factor for leukemia, especially long-term use of older coloring products. Am J
Epidem July 1, 2004.

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of publications.
Cancer researchers observed the incidence of certain cancers in some areas is lower than in other areas of
the world. One example is Mediterranean area. As nutrition and dietary factors comprise one of the major
factors for cancers. Inspecting their dietary profile, Mediterranean diet is rich in antioxidants. Those living in
the mountaineous area of Finland ile. Mountain are also found to have low occurence and mortaility from
coronary heart disease and cancer.  They have high serum antioxidants, alpha tocopherol, albumin and
selenium levels. Thus, some scientists believe that certain diets have "anti-cancer" or at least "cancer
prevention" properties.
Anti-cancer diet