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[Widipedia 01/29/11] Shea butter is a slightly yellowish or ivory-colored natural fat
extracted from the nut of the African shea tree (Vitellaria paradoxa) by crushing, boiling
and stirring. It is widely used in cosmetics as a moisturizer, salve or lotion.
[FDA Website - MAUDE Adverse Event Report 01/29/11] Event Date 08/01/2008 This
spontaneous report of a non-serious, unlabeled event (rash) is being submitted as a
10-day report. A female consumer reported that she received injections of restylane
injectable gel (injectable dermal filler) into her upper lip and above the lip in 2008. Medical
history included 2 previous restylane treatments (2007, 2008, approximately 6 months
apart) in which cold sores developed post treatment. Concomitant medications were not
reported. On an unspecified date approximately 1 week post injection, the patient's face
became dry (dry skin) and pink. The next day the patient developed a severe red
(erythema) blotchy rash (rash) all over her face. Her face was itchy (pruritus), and swollen
(swelling face), one of her eyes was swollen shut and her lip were swollen (implant site
swelling). The patient applied an unspecified "facial lotion" (ingredients included shea
butter, jojoba, aloe vera) she had on hand and stated it made the symptoms worst. The
patient was seen by a plastic surgeon (not the injecting physician) who prescribed atarax
(hydroxyzine) and an oral steroid dose pak. The symptoms resolved within a day or two.
The patient reported the physician stated the rash was probably caused by the restylane,
though it was unusual for it to develop a full week after the treatment.
[J Pharm Belg. 2003;58(3):81-4] A shea butter ointment containing 3% aureomycin was
prepared. Then, the release of the active ingredient was compared with those made of
petroleum jelly and lanoline. It was shown that the shea butter ointment had satisfactory
characteristics. In the other hand, it was found that shea butter released the aureomycin
easily and at a faster rate than the other excipients.
[J Oleo Sci. 2010;59(6):273-80] The biological activities of triterpene acetate and
cinnamate esters, together with the exceptionally high levels of these triterpenes in shea
fat, indicate that shea nuts and shea fat (shea butter) constitute a significant source of
anti-inflammatory and anti-tumor promoting compounds. Thus, shea butter may have
health benefit of lowering the risk of inflammation and cancer. But, more studies are
needed to support this claim of health benefits.