Does aspirin raise blood pressure?
Potential health benefits and research finds   2007
Regular use of popular painkillers such as aspirin and ibuprofen increases the risk of
heart disease in men by raising blood pressure, a research suggests.
[1] Long-term data needed on anti-obesity drugs Reuters Fri Jan 5, 12:19 PM ET 2007 [2] Sjostrom L. Analysis of the XENDOS study (Xenical in the Prevention of Diabetes in
Obese Subjects). Endocr Pract. 2006 Jan-Feb;12 Suppl 1:31-3. Torgerson JS, Hauptman J, Boldrin MN, Sjostrom L. XENical in the prevention of diabetes in obese subjects
(XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care. 2004
Jan;27(1):155-61[3] Use of orlistat (xenical) in the treatment of women with obesity and disorders of menstrual cycle Georgian Med News. 2006 Oct;(139):20-2. [4] Ametov
AS, Demidova TIu, Tselikovskaia AL. Complex assessment of metabolic parameters in obese patients treated with xenical Ter Arkh. 2004;76(1):49-53. [5]  FDA Consumer
Information Revised: 11/16/00
Dr John Forman of Brigham from Women's Hospital in Boston looked at
16,000 men, checking records over a four-year period and he found that
men who take painkillers most days a week are a third more likely to be
diagnosed with high blood pressure.

According to the study, men who took acetaminophen (paracetamol, or
Tylenol), six or seven days a week were 34 percent more likely to be
diagnosed with high blood pressure than non-users.

Men who took aspirin that regularly were 26 percent more likely to have high
blood pressure than men who did not take analgesics. While the increased
risk for ibuprofen and naproxen was 38 percent.

Is it a cause-effect relationship or just a correlation?

Looked at another way, perhaps those men who suffer from high blood
pressure are more likely to take or feel the need to take painkillers. Which
came first, the high blood pressure or the taking of painkillers? Scientists
have actually done some experiments on this issues:

Aspirin lowers blood pressure at bedtime.


Reference Update 1-Common painkillers raise blood pressure-study Reuters Feb 26, 2007
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