Does aspirin raise blood pressure?
Potential health benefits and research finds   2007
Regular use of popular painkillers such as aspirin and ibuprofen increases the risk of
heart disease in men by raising blood pressure, a research suggests.
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[1] Long-term data needed on anti-obesity drugs Reuters Fri Jan 5, 12:19 PM ET 2007 [2]
Sjostrom L. Analysis of the XENDOS study (Xenical in the Prevention of Diabetes in Obese
Subjects). Endocr Pract. 2006 Jan-Feb;12 Suppl 1:31-3. Torgerson JS, Hauptman J,
Boldrin MN, Sjostrom L. XENical in the prevention of diabetes in obese subjects (XENDOS)
study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of
type 2 diabetes in obese patients. Diabetes Care. 2004 Jan;27(1):155-61[3] Use of orlistat
(xenical) in the treatment of women with obesity and disorders of menstrual cycle Georgian
Med News. 2006 Oct;(139):20-2. [4] Ametov AS, Demidova TIu, Tselikovskaia AL. Complex
assessment of metabolic parameters in obese patients treated with xenical Ter Arkh.
2004;76(1):49-53. [5]  FDA Consumer Information Revised: 11/16/00
Dr John Forman of Brigham from Women's Hospital in Boston
looked at 16,000 men, checking records over a four-year
period and he found that men who take painkillers most days a
week are a third more likely to be diagnosed with high blood
pressure.

According to the study, men who took acetaminophen
(paracetamol, or Tylenol), six or seven days a week were 34
percent more likely to be diagnosed with high blood pressure
than non-users.

Men who took aspirin that regularly were 26 percent more likely
to have high blood pressure than men who did not take
analgesics. While the increased risk for ibuprofen and
naproxen was 38 percent.

Is it a cause-effect relationship or just a correlation?

Looked at another way, perhaps those men who suffer from
high blood pressure are more likely to take or feel the need to
take painkillers. Which came first, the high blood pressure or
the taking of painkillers? Scientists have actually done some
experiments on this issues:

        
Aspirin lowers blood pressure at bedtime.


Reference Update 1-Common painkillers raise blood pressure-study Reuters
Feb 26, 2007