Orlistat, Alli and Xenical
side effects
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The only over-the-counter drug for weight loss that has been approved by the FDA is being
reviewed by the agency after reports suggested the drug, orlistat, may cause liver damage. [1]

More than 30 reports to FDA said that patients taking Alli and Xenical. Xenical is the
prescription form of the pill. Many wound up hospitalized for their condition, while six patients
were treated for liver failure. [1]

Glaxo sells the nonprescription version under the brand name alli. The company said in a
statement "there is no evidence that alli causes liver damage," which can stem from many
causes. People who are overweight or obese are predisposed to liver-related disorders, the
company said. [2]

Alli (Orlistat 60 mg Capsules)

Claim: Weight Loss Aid

Typically, enzymes in your intestines break down fat from food so your body can absorb the fat.
But the active ingredient in alli attacks to some of these enzymes and prevents them from
digesting about a quarter of the fat you eat. Because undigested fat can't be absorbed, it
passes out of your body instead of turning into calories.

Common Side Effects:  The oily stuff sticks to your toilet; it is hard to clean. In addition, if you
intake a lot of grease food, you may experience an urgent need to go to bathroom. It can prove
potentially embarrassing and uncomfortable; some oily bowel may leak out. Even though Alli is
specifically structured to take out the fatty content of dietary intake, It may also prevent the
absorption of fat-soluble vitamins.

Good thing is.. because of the embarrassing situation and the urgent needs to go to bathroom,
most of the users become self-motivated to cut out the fatty diets.

Patients should not use alli if they are pregnant or breast-feeding, have had an organ transplant
or taking medicines to prevent rejections, have problems absorbing food, or are not overweight.

[1] Health Buzz: Weight-Loss Drug Faces FDA Review and Other Health News U.S. News
August 25, 2009

[2] U.S. Probes Roche, Glaxo Diet Drug Over Liver Injury ABC News, August 24, 3009.